Generic for Flomax

Generic for flomax is specific blocker of postsynaptic adrenoreceptors, being in smooth muscle of prostate gland, neck of urinary bladder and prostatic urethral part. Blockade of alfa-adrenoreceptors results with flomax generic to decrease of tone of smooth muscle of prostate gland, bladder neck and prostatic urethral part and improvement of outflow of urine. Symptoms of obstruction and irritation, connected with good-quality prostate hypertrophia simultaneously decrease. Such image, generic for flomax improves outflow of urine, increases speed of stream of urine and reduces level of symptoms of disease. Ability flomax pill to influence on alfa-adrenoreceptors in 20 time exceeds it ability to interact with alfa-adrenoreceptors, that are located in vascular smooth muscles. Does not cause some clinically meant decrease of system blood pressure due to such high selectivity of generic flomax how at patients with hypertension, so and at patients with normal initial blood pressure.

Tamsulosin is quickly and practically completely absorbed from GKT at reception inside. Bioavailability preparation about 100 %. After single administration inside 0.4 mg of preparation of it maximum concentration reach in plasma through 6 hours. Linkage with fibers of plasma of 99 %. Preparation is not subject to to "effect of first passage" and slowly metallization in liver with formation of pharmacologically active metabolities, keeping high selectivity to alfa-adrenoblockers. Is deduced with kidneys, selected to 9 % of preparation in unaltered kind. Period of semiejection of preparation at single administration 10 hours, final half of life - 22 hour. It how corrected, therapeutic effect is developed through 2 weeks after beginning of intake of the preparation.

It is not noted cases of sharp overdosage generic for flomax. Symptoms. There theoretically exists probability of occurrence of sharp arterial hypotension after overdosage flomax and compensatory tachycardia, that can require application of measures for maintenance of functions of intimate-vascular system (cardiotropic therapy). Treatment. It is neccessary to place the patient; If symptoms of hypotension remain, it is necessary to enter solutions or vasoconstrictive preparations. For prevention of far suction generic for flomax gastric lavage, reception of activated coal or osmotic purgative are possible (sodium sulfate). It is necessary to check renal function. Application of haemodialysis is inefficient in connection with high degree of linkage generic for flomax with fibers of blood plasma.